Bumetanide interferes with renal cAMP and/or inhibits the sodium-potassium ATPase pump. Bumetanide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule. This results in excretion of sodium, chloride, and water and, hence, diuresis.
Bumetanide-induced fluctuations in serum electrolyte concentrations can occur rapidly and precipitate serious hepatic effects in susceptible patients, including hepatic encephalopathy and/or coma. Bumetanide should be used with caution in patients with significant hepatic disease such as cirrhosis with ascites.
Summary of Interactions with Vitamins, Herbs, & Foods. What Are Nutrient Interactions. Types of interactions: Beneficial Adverse Check. Replenish Depleted Nutrients Magnesium and Potassium. List of Drug Approvals by the Medicines Control Council in South Africa containing Bumetanide on PharmaCompass.com. Drug Approvals by the Medicines Control Council in South Africa containing Brand Name Burinex 1 mg.
Drug class (es): loop diuretics. Bumetanide systemic is used in the treatment of: Ascites. Autism. Edema.
Bumetanide is known as a diuretic (the same kind of drug as a "water pill "). It causes your body to get rid of extra water by increasing the amount of urine you make. Bumetanide is available under the following different brand names: Bumex, and Burinex.
Bumetanide interferes with renal cAMP and/or inhibits the sodium-potassium ATPase pump. Bumetanide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.
2021-01-21
Basics. Name. Bumetanide. Pronunciation (byoo MET a nide) Brand Names: US. You are authorized to use the AAP’s trademarks, logos and brand names Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in patients in whom high doses of furosemide are ineffective.
A high bumetanide. U.
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Bumetanide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.
Autism. Edema.
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Therefore, careful medical supervision is required, and dose and dosage schedule have to be adjusted to the individual patient's needs (see DOSAGE AND ADMINISTRATION ). 341 Bumetanide this is brand name Bumex a diuretic commonly used to treat CHF from MED MISC at Grand Canyon University Bumetanide-induced fluctuations in serum electrolyte concentrations can occur rapidly and precipitate serious hepatic effects in susceptible patients, including hepatic encephalopathy and/or coma. Bumetanide should be used with caution in patients with significant hepatic disease such as cirrhosis with ascites.
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Learn more about Bumetanide And Potassium Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in patients in whom high doses of furosemide are ineffective. There is however no reason not to use bumetanide as a first choice drug. The main difference between the two substances is in bioavailability. Bumetanide Maximum dosage Up to 10 mg/day has been used in adults with normal renal function. (15) Up to 20 mg/day has been given to adults with renal dysfunction.(15) Additives Benzyl alcohol.(2) (See Appendix C for specific information about potential benzyl alcohol toxicity.) Suitable diluents D5W, LR, or NS(2,17) Maximum concentration Bumetanide (brand name Bumex) is a loop diuretic. It is one of the Top 250 Drugs (similar to the Top 200 Drugs or Top 300 Drugs) in ClinCalc.com's RxHero mobile app, FlashRX mobile app and The Top 250 Drugs online educational video course.
Bumetanide ≥98% Synonym: 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid CAS Number 28395-03-1. Empirical Formula (Hill Notation) C 17 H 20 N 2 O 5 S . Molecular Weight 364.42 . EC Number 249-004-6. MDL number MFCD00078949. PubChem Substance ID 24278265. NACRES NA.77
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It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine. View all Brand Names Innovator's Monograph Indications Bumetanide is indicated for the treatment of edema associated with- Congestive heart failure, Hepatic ascites and, Renal disease including the nephrotic syndrome Bumetanide Oral tablet 0.5mg Drug Medication Dosage information.